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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 55, Number 6
JKCSEZ 55(6)
December 20, 2011

Title	Studies on Some Bioactive 1,1-Bis(2-benzylidene-5-aryliden-1,3-thiadiazolidin-4-one)cyclopropane
Author	Hemant Panwar*, Nidhi Chaudhary, Sachi Singh, Amit Chawla
Keywords	Bis-phenylarylidinylthiadiazolidinone cyclopropane, Antifungal, Antibacterial, Acute toxicity
Abstract	Some novel heterocyclic derivatives of 1,1-bis(2-phenyl-5-arylidine-1,3-thiadiazolidin-4-one)cyclopropane 4(a-i) have been synthesized from cyclopropane dicarboxylic acid and substituted thiadiazole moieties. All the synthesized compounds have been characterized by elemental and spectral (I.R., 1H-NMR, Mass) analysis. Furthermore, above said compounds were screened for their antifungal and antibacterial activities. Compound 4c was found the most potent one which further evaluated for lesser toxicity test.
Page	994 - 999
Full Text	PDF

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