ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 52, Number 3
JKCSEZ 52(3)
June 20, 2008 

The synthesis, characterization and bioevaluation of five new tetrahydroquinazolines was reported. Initially cyclohexanones were prepared and they were used as synthons to get the target molecules. These were condensed with substituted benzaldehydes and the resulting chalcones were treated with guanidine hydrochloride . All the molecules were non-toxic to human cells and showed significant antibacterial activity.