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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 19, Number 3
BKCSDE 19(3)
March 20, 1998

Title	Synthesis and Fungicidal Activity of 1-[(1H-1,2,4-triazol-1-yl)alkyl]-1-silacyclohexanes
Author	Bok Ryul Yoo, Mi Yeon Suk, Yong-Man Yu, Soon-Gyu Hong, Il Nam Jung
Keywords
Abstract	A series of six-membered ring organosilicon compounds, 1-aryl-1-(1H-1,2,4-triazol-1-yl)alkyl-1-silacycloh exanes 3a-c, have been synthesized by four-step reactions starting from 1-(chloroalkyl)trichlorosilanes. Their fungicidal activities were tested in in vitro for ten fungi and in vivo assay for four fungi occurring in rice, barley, tomato, and etc. and compared with the flusilazole. Especially, 1-p-fluorophenyl-1-[1-(1H-1,2,4-triazol-1-yl)alkyl ]-1-silacyclohexanes (3a, alkyl=methyl; 3b, alkyl=ethyl) showed good fungicidal activity with broad spectrum close to the flusilazole in in vivo assay.
Page	358 - 362
Full Text	PDF

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