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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 18, Number 5
BKCSDE 18(5)
May 20, 1997

Title	Synthesis of 4H,6H-Furo[3,4-c]isoxazole Derivatives as New Potent Fungicides and Their Structure Activity Relationship
Author	Hyung Jin Kim, Kwang-Jin Hwang, Jae Hyun Lee
Keywords
Abstract	4H,6H-Furo[3,4-c]isoxazoles (Ⅰ-Ⅳ), potential fungicides, have been designed and synthesized via intramolecular [2+3] cycloaddition of nitroalkyne 3 as a key step. The broad spectrum of fungicidal activities of furoisoxazoles (Ⅰ-Ⅳ) were observed on plant pathogens at 250 ppm. Furoisoxazoles Ⅱ, Ⅲ with chlorophenyl at 6-position and methyl or alkylated oxime group at 3-position gave effective control of plant diseases. The furoisoxazole Ⅳ with a chlorophenyl group at 4-position also resulted in high fungicidal activities.
Page	534 - 540
Full Text	PDF

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