Current time in Korea 19:57 Sep 15 (Sun) Year 2019 KCS KCS Publications
KCS Publications
My Journal Log In Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 16, Number 11
BKCSDE 16(11)
November 20, 1995 

 
Title
Synthesis and Properties of Novel Pt(Ⅱ)-containing Polyphosphazenes
Author
Hyounggee Baik, Ok-Sang Jung, Yong Kiel Sung, Youn Soo Sohn*
Keywords
Abstract
Poly(dichlorophosphazene) having low molecular weight (M&bar;w∼104) was synthesized by the thermal reaction of hexachlorocyclotriphosphazene in the presence of excess AlCl3 (>2%) as catalyst. Using the poly(dichlorophosphazene), poly[bis(ethylglycino)phosphazene], poly[bis(glycinemethylamido)phosphazene], and poly[(glycinemethylamido)(methylamino)phosphaze ne] were prepared. Diammineplatinum(Ⅱ) complex cation was introduced into these derivatized phosphazene polymers, and the resultant polymers containing the platinum(Ⅱ) moiety were charaterized by means of elemental analysis, IR and NMR spectroscopies, and then subjected to in vitro and in vivo assays of antitumor activity.
Page
1074 - 1079
Full Text
PDF