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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 14, Number 3
BKCSDE 14(3)
March 20, 1993 

Ultraviolet Light-induced Lipid Peroxidation of Cultured Skin Fibroblast Membrane
Seh Hoon Kang, Quae Chae*
UVA (320-400 nm) light-induced lipid peroxidation was investigated in the cultured human fibroblast membrane. The main reactive oxygen species (ROS) involved in the process were identified as the partially-reduced oxygen species(superoxide radical, hydrogen peroxide and hydroxyl radical) rather than singlet oxygen. It was found that the amount of reactive oxygen species produced by UVA in extracellular matrix was not sufficient to cause membrane lipid peroxidation. The effectiveness for protection of skin from UVA induced damage was found by using scavengers and/or terminators for these oxygen species.
371 - 374
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