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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 12, Number 6
BKCSDE 12(6)
June 20, 1991 

 
Title
C-Glucuronide from O-Glucuronyl Trichloroacetimidate
Author
Seung-Hwa Baek
Keywords
Abstract
From O-glucuronyl trichloroacetimidate (4) and △ 6-tetrahydrocannabinol (5), the C-glucuronide of △6-tetrahydrocannabinol(△6-THC) (7) was obtained using mild Lewis acid catalysis. The known method for the synthesis of C-glucuronide from 1-O-unprotected glucuronide provided low chemical yields. The C-glucuronide of △6-THC was obtained through inversion of configuration at the anomeric center in O-glucuronyl trichloroacetimidate (4).
Page
604 - 606
Full Text
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