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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 35, Number 2
BKCSDE 35(2)
February 20, 2014 

Synthesis and Bioactivity of Quercetin Aspirinates
Chenjuan Lu, Feng Huang, Zexin Li, Jinshuo Ma, Huanhuan Li, Lizhen Fang*
Quercetin, Polyphenol, Esterification, Quercetin aspirinates, Bioactivity
Hybrids of some natural compounds are promising to obtain new leads with good biological activities for drug discovery. Three quercetin aspirinates were synthesized by esterification of the 3-and 7-hydroxyl groups of quercetin with aspirin. Biological activities of these quercetin aspirinates were initially screened and showed better cytotoxic activities against tumor cell lines HL-60 and HepG2 and less scavenging activity against DPPH than the quercetin respectively.
518 - 520
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