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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 34, Number 11
BKCSDE 34(11)
November 20, 2013 

 
Title
Two New Diphenylethylenes from Arundina graminifolia and Their Cytotoxicity
Author
Yin-Ke Li, Bin Zhou, Yan-Qing Ye, Gang Du, De-Yun Niu, Chun-Yang Meng, Xue-Mei Gao*, Qiu-Fen Hu*
Keywords
Arundina graminifolia, Diphenylethylenes, Structure elucidation, Cytotoxicity
Abstract
Two new diphenylethylenes, gramniphenols H and I (1 and 2), together with six known diphenylethylenes (3- 8), were isolated from Arundina graminifolia. The structures of 1-8 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1 and 2 were evaluated for their cytotoxicity against five human tumor cell lines. Compound 1 showed cytotoxicity against PC3 cells with IC50 value of 3.5 μM. Compound 2 showed cytotoxicity against NB4 and PC3 cells with IC50 values of 3.6 and 3.8 μM, respectively.
Page
3257 - 3260
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