Current time in Korea 00:19 Apr 27 (Sat) Year 2024 KCS KCS Publications
KCS Publications
My Journal  Log In  Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 33, Number 4
BKCSDE 33(4)
April 20, 2012 
 
Title
 Structure-Guided Identification of Novel Phenolic and Phenolic Amide Allosides from the Rhizomes of Cimicifuga heracleifolia
Author
 Soon-Ho Yim, Hyun Jung Kim, Nari Jeong, Ki Deok Park, Young Ju Lee, Sung Dong Cho, Ik-Soo Lee*
Keywords
 Cimicifuga heracleifolia, cis-Ferulic acid 4-O-β-D-allopyranoside, trans-Ferulic acid 4-O-β-Dallopyranoside, trans-Feruloyltyramine 4-O-β-D-allopyranoside, trans-Feruloyl-(3-O-methyl)dopamine 4-O- β-D-allopyranoside
Abstract
 Two phenolic allopyranosides and two phenolic amide allopyranosides, along with eight known phenolic compounds, including cimicifugic acids, shomaside B, fukiic acid, isoferulic acid, and piscidic acid, were isolated from the n-butanolic extract of rhizomes of Cimicifuga heracleifolia. On-line spectroscopic data for UV, NMR, and MS from a combination of LC-NMR and LC-MS techniques directly and rapidly provided sufficient structural information to identify and confirm all the structures of major phenolic compounds in the extract, in addition to their HPLC profiles. This combined analytic information was then used as a dereplication tool for structure-guided screening in order to isolate unknown phenolic compounds in the extract. Successive fractionation and purification using semi-preparative HPLC acquired four unknown allopyranosides, and their structures were identified as cis-ferulic acid 4-O-β-D-allopyranoside, trans-ferulic acid 4-O-β-D-allopyranoside, trans-feruloyltyramine 4-O-β-D-allopyranoside, and trans-feruloyl-(3-O-methyl)dopamine 4-O-β-D-allopyranoside, based on a subsequent spectroscopic interpretation.
Page
 1253 - 1258
Full Text
 PDF / Supporting Information

How to access to the WOL for The Bulletin of the Korean Chemical Society ?

The Bulletin of the Korean Chemical Society will be co-published with Wiley-VCH from 2015 towards. The online version of the Journal will thus be available on Wiley Online Library, Wiley(-VCH)'s global online platform.

KCS members can get a free online access to the Bulletin of the Korean Chemical Society in WOL.

Close