KCS Publications

HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 30, Number 9
BKCSDE 30(9)
September 20, 2009

Title	Application of Cl3CCONH2/PPh3 towards the Synthesis of Bioactive Amides
Author	Skydow Chaysripongkul, Wanchai Pluempanupat, Doo Ok Jang, Warinthorn Chavasiri
Keywords	Trichloroacetamide, Triphenylphosphine, Chlorinating agent, Amide
Abstract	Cl₃CCONH₂ coupled with PPh₃ was determined to be an effective reagent for the conversion of carboxylic acids to their corresponding acid chlorides. Subsequently, these acid chlorides were successfully trapped with amines in the presence of 4-picoline, yielding amides. This practical and efficient protocol can be utilized for the synthesis of biological amides in excellent yields.
Page	2066 - 2070
Full Text	PDF

How to access to the WOL for The Bulletin of the Korean Chemical Society ?

The Bulletin of the Korean Chemical Society will be co-published with Wiley-VCH from 2015 towards. The online version of the Journal will thus be available on Wiley Online Library, Wiley(-VCH)'s global online platform.

KCS members can get a free online access to the Bulletin of the Korean Chemical Society in WOL.

Free Access to WOL