Current time in Korea 01:35 Feb 29 (Sat) Year 2020 KCS KCS Publications
KCS Publications
My Journal Log In Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 29, Number 12
BKCSDE 29(12)
December 20, 2008 

Kinetics and Mechanism for the Formation of b- and y-type Ions from Singly Protonated Peptides on a Microsecond Time Scale: The Arginine Mystery
Yeon Ji Chung, So Hee Yoon, Myung Soo Kim*
Oxazolone pathway, b-y Ions, RRKM, Arginine
A kinetic model was built for the formation of b and y ions ? which are the main product ions generated from singly protonated peptides at low internal energy regime ? on a microsecond time scale based on the potential energy diagram along the oxazolone pathway reported previously. The rate constants were evaluated using the Rice-Ramsperger-Kassel-Marcus theory. Even though migration of the extra proton to an amide nitrogen is a prerequisite in the oxazolone mechanism, it was found highly unlikely when this proton was sequestered at an arginine side chain. Possibility of migration of a proton from other locations such as a carboxyl group is discussed.
2427 - 2433
Full Text