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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 29, Number 10
BKCSDE 29(10)
October 20, 2008

Title	Approaches to the Syntheses of Partially Reduced Imidazo[1,2-a]pyridines
Author	Junhwa Shin*, Young Chang Nho, Arthur S Howard
Keywords	Aza-alkaloid, Heterocyclic compounds, Indolizidine
Abstract	Two synthetic pathways to substituted hexahydroimidazo[1,2-a]pyridines, which may serve as precursors of aza-alkaloids, were investigated. The first involves the condensation of a bisnucleophilic enediaminoester and a biselectrophile. The second involves attachment to nitrogen of the carbon chain skeleton required to form the six-memberd ring, before formation of the enediaminoester. Several substituted hexahydroimidazo[1,2- a]pyridines were synthesized via these two approaches.
Page	1998 - 2004
Full Text	PDF

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