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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 28, Number 4
BKCSDE 28(4)
April 20, 2007 

The Influence of Bioactive Inorganic Materials on Osteopontin Expression in Rat Calvarial Osteoblast Culture
Byung Bae Mun, Kyoung Hwa Jung, Young Gyu Chai, Ho Kun Kim*
Hydroxyapatite, Tricalcium phosphate, Titanium, Osteopontin expression
Hydroxyapatite [Ca10(PO4)6(OH)2, HAp] and titanium(Ti) metal are known to be excellent materials with high affinities for natural bone through the apatite. Tricalcium phosphate [Ca3(PO4)2, TCP] is a promising alternative material because it is similar to HAp in its physical properties and biocompatibility. To examine the influence of hydroxyapatite, tricalcium phosphate, pure titanium and pre-treated titanium on osteopontin expression in osteoblasts, RNA was extracted from proliferated and cultured osteoblast cells and OPN mRNA expression was observed by RT-PCR.
652 - 656
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