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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 25, Number 10
BKCSDE 25(10)
October 20, 2004 

The Inhibitory Effect of Prunioside A Acyl Derivatives on NO Production in RAW 264
Woo-Yiel Lee, Byung Hee Kim, Young Hang Lee, Han Gil Choi, Byung Hun Jeon, Seon Il Jang, Young-Jun Kim, Hun Taeg Chung, Young Soon Kim, Kyu-Yun Chai*
Spiraea prunifolia, Prunioside A, Nitric oxide, NO production, Inhibitory effects
Prunioside A is a unique, highly oxidized monoterpene glycoside isolated from the methanol extract of Spiraea prunifolia var. Simpliciflora's root. The ester derivatives were synthesized from the hydrolyzed compounds of prunioside A by β-glucosidase. The derivatives showed suppressive effects on the generation of nitric oxide in murine machrophage-like RAW 264.7 cells stimulated by lipopolysaccharide and interferon- γ.
1555 - 1558
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