ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 37, Number 9
JKCSEZ 37(9)
June 20, 1993 

3-Cyanopyridine, when treated with organolithium or Grignard reagents, gives addition to the 6-position and provides a series of 2-substituted 5-cyanopyridines (6-substituted 3-cyanopyridines). Alternatively, 2-and 4-cyanopyridine react with CH3Li or CH3MgI and provide 2-acetylpyridine and 4-acetylpyridine, respectively.