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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 42, Number 1
JKCSEZ 42(1)
February 20, 1998 

 
Title
Anthraquinones and Sterols from the Korean Marine Echiura Urechis unicintus

한국산 해양 의충동물 개불에서 Anthraquinone 및 Sterol 성분 연구
Author
Sungkeun Chang*, Yonghyun Park, Seuk Chai, Inkyu Kim, Youngwan Seo, Kiwoong Cho, Jongheon Shin

장성근, 박영현, 채 석, 김인규, 서영완, 조기웅, 신종헌
Keywords
Abstract
한국 연해에 서식하고 있는 의충동물 개불(Urechis unicintus)로부터 강심작용과 관련된 Na+, K+-ATPase 저해 작용 및 AMP phosphodiesterase 저해 작용이 높은 anthraquinones화합물인 chrysophanol, physcion 및1-o-methyl-2-methoxychrysophanol을 분리하였다.주로 HMQC, HMBC 및 NOE 등의 분광학적 방법으로 이들의 구조를 밝혔다.

Three anthraquinones, chrysophanol, physcion and 1-o-methyl-2-methoxychrysophanol which have Na+, K+-ATPase and cyclic AMP phosphodiesterase lowering activities related to cardiotonic action were isolated from the Korean marine echiura, Urechis unicintus. Spectroscopic methods, including HMQC, HMBC and NOE studies, were used to establish the structures.

Page
64 - 68
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