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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 40, Number 4
JKCSEZ 40(4)
August 20, 1996 

 
Title
Synthesis of New 5-Benzyl-4-cyanomethyl-2-methylpyrimidine Derivatives

새로운 5-Benzyl-4-cyanomethyl-2-methylpyrimidine 유도체들의 합성
Author
Jung-Hwan Kim, Mun-Su Hah

김정환,한문수
Keywords
Abstract
5-Benzyl-4-cyanomethyl-2-methylpyrimidine의 6번 위치에 chloro, methoxy, ethoxy, phenoxy, anilino기가 도입된 새로운 유도체(5)들의 합성은 5-benzyl-4-chloro-2-methylpyrimidine 유도체(3)들과 tert-butylcyanoacetate로부터 합성되었으며, 5-benzyl-4-chloro-2-methylpyrimidine의 6번 위치에 chloro, methoxy, ethoxy, phenoxy, anilino기가 도입된 새로운 유도체(3)들은 5-benzyl-4,6-dichloro-2-methylpyrimidine(2)로부터 합성되었다.

The synthesis of new 5-benzyl-4-cyanomethyl-2-methylpyrimidine derivatives (5) containing chloro, methoxy, ethoxy, phenoxy and anilino groups at 6-position on the pyrimidine ring were prepared from 5-benzyl-4-chloro-2-methylpyrimidine derivatives (3) and tert-butylcyanoacetate. The derivatives of 5-benzyl-4-chloro-2-methylpyrimidine (3) containing chloro, methoxy, ethoxy, isopropoxy, phenoxy and anilino groups at 6-position on the pyrimidine ring were prepared from 5-benzyl-4,6-dichloro-2-methylpyrimidine (2).

Page
249 - 253
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