ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 20, Number 1
JKCSEZ 20(1)
February 20, 1976 

The crystal structure of alicylaldehyde-4-piperidinothiosemicarbazone, C13Hl7N3OS, has been determined by single crystal X-ray analysis. The crystals are orthorhombic, space group P212121, with unit cell dimensions a = 6.52(2), b = 13.42(4), c = 14.92(4)Å. There are four formular units in a unit cell. The structure was solved by the heavy atom method and refined by isotropic block diagonal least-squares methods to a final R value of 0.10 for 1019 observed reflections. The oxygen atom of the hydroxyl group is involved in two hydrogen bonds, one as donor in the intramolecular O-H…N hydrogen bond and the other as acceptor in the intermolecular N-H…O hydrogen bond, the distances of the hydrogen bonds 2.56 and 3.00Å respectively.The molecules are joined into infinite columns by the N-H…O hydrogen bonds which form spirals along the two fold screw axis parallel to the a axis. The molecular columns are held together by van der Waals forces.