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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 14, Number 3
JKCSEZ 14(3)
June 20, 1970 

 
Title
Synthesis of 2,6-dichloro-4-Nitro Aniline Mercuric Acetate and Its Pharmaceutical Effects
Author
Chul Hyung Cho, Sungeuy Shin
Keywords
Abstract
A large variety of weed killers, insecticides, and bactericides on the market today are of almost infinite variety, but their pharmacological effects are different from each other according to the objects to cope with. Therefore, it is hoped that some chemical substance which serves as weed killer, an insecticide, and a bactericide at a same time, should be synthesized, in order to save expense and labor. I anticipated that the desire would be met by introducing to a molecule the radical which has the three effects. Here, I made an attempt of introducing Cl2 gas to aniline considering the following respects:1. Introduction velocity of Cl2 gas under the varied temperatures and velocities of Cl2 gas 2. The effect of reaction period under the condition which gives the most satisfactory yield. 3. The actions of catalysts, SbCl3, FeCl3, and MoCl5, and their proportions when a mixture of the three catalysts is used in producing 2,6-dichloro-aniline. After consideration of above phenomena, the maximum production rate of 79.5% of 2,6-compound was obtained. With the compound Ⅰ synthesized 2,6-dichloro-4-nitroaniline-mercuric acetate. Investigations of the effects of the compound as weed killer, an insecticide, and a bactericide showed that the compound, 2,6-dichloro-4-Nitro Aniline mercuric Acetate has a satisfactory herbi-insecti-bactericidal effect.
Page
207 - 212
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