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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 14, Number 2
JKCSEZ 14(2)
April 20, 1970

Title	Radioiodination-Ⅳ & Ⅴ-Study on the radioiodination of organic compounds by a hydrogen peroxide procedure 방사성요오드화반응-Ⅳ,Ⅴ보-과산화수소를 이용한 요오드표지 합성법의 검토
Author	You sun Kim, Tae young Kim 김유선, 김태영
Keywords
Abstract	A study was made on the radioiodination of organic compounds in presence of hydrogen peroxide both in aqueous and organic solvent systems. In case of the reaction of rosebengal, Hippuran, and 5-iodo-uracil the aqueous reaction system could give high labelling yield within a relatively short reaction time. Labelling yield of average 50% could be obtained within 30 minutes of reaction sequence. In cases of organic solvent systems (D.M.S.O., D.M.F., and Dioxane) the solvent system of D.M.S.O. could give better yield for neutral organic compounds, where as D.M.F. and Dioxan gave better labelling result for acidic materials. Especially, o-iodobenzoic acid, o-iodotoluene, and pentachlorophenol could be labelled better in organic solvent system.
Page	169 - 177
Full Text	PDF

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