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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 57, Number 4
JKCSEZ 57(4)
August 20, 2013 

 
Title
One Pot Synthesis of Bioactive Novel Cyanopyridones
Author
Kamlesh Khokhani, Taslimahemad Khatri*, Praful Patel
Keywords
Cyanopyrimidones, Cyanoacetamide, Antimicrobial activity, Malononitrile, Pipyridine
Abstract
Cyanopyridone was prepared by the condensation of cyanoacetamide, substituted arylaldehydes and malononitrile in presence of pipyridine. The structure of the synthesized compound CP 1-20 was assigned on the basis of elemental analysis, IR, 1H-NMR and mass spectroscopy. These compounds were also screened for antimicrobial activity. The Minimum Inhibitory Concentration (MIC) of all the synthesized compounds was compared with standard drugs.
Page
476 - 482
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