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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 57, Number 4
JKCSEZ 57(4)
August 20, 2013 

Synthesis and Biological Evaluation of 2-Amino-4H-pyran-3,4,5-tricarboxylate Salt Derivatives
Ali Akbari*, Zabihollah Azami Sardooei, Asghar Hosseini Nia
Biological evaluation, Antibacterial activity, 4H-Pyran-3,4,5-tricarboxylate, BF3.SiO2
A novel and simple method for the synthesis of 2-amino-4H-pyran-3,4,5-tricarboxylate derivative and the evaluation of their antibacterial activity against Pseudomonas syringae, Xanthomonas citi and Pectobacterium carotovorum are reported. The structure of the isolated compounds has been determined by means of 1H/13C NMR and FT-IR Spectroscopy. The reaction of alkyl isocyanides with acetylenic esters in the presence of dimethyl acetone-1,3-dicarboxylate in the present of BF3.SiO2 at ambient temperature. Some of the compound showed significant inhibition to growth of bacteria.
455 - 460
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