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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 57, Number 2
JKCSEZ 57(2)
April 20, 2013 

 
Title
ZrOCl2·8H2O as an Efficient Catalyst for the Pseudo Four-Component Synthesis of Benzopyranopyrimidines
Author
Hamid Reza Tavakoli, Sayed Mojtaba Moosavi, Ayoob Bazgir*
Keywords
Solvent-free, Malononitrile, Benzopyranopyrimidine, Salicylaldehyde
Abstract
An efficient and environmentally benign protocol for the pseudo four-component synthesis of benzopyranopyrimidines via condensation of salicylic aldehydes, malononitrile and various amines catalyzed by ZrOCl2·8H2O as an inexpensive and eco-friendly catalyst with high catalytic activity under solvent-free conditions is reported. This protocol provides a new and improved method for obtaining benzopyranopyrimidines in terms of good yields, simple experimental procedure and short reaction time.
Page
260 - 263
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