Current time in Korea 06:24 Dec 01 (Tue) Year 2020 KCS KCS Publications
KCS Publications
My Journal  Log In  Register
HOME > Search > Browsing(JKCS) > Archives

Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 57, Number 2
JKCSEZ 57(2)
April 20, 2013 

 
Title
Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives
Author
Yellappa Shivaraj, Malenahalli H Naveen, Giriyapura R Vijayakumar*, Doyijode B Aruna Kumar
Keywords
Quinoline-6-carboxamides, 2-Chloro quinoline-4-carboxamides, Antibacterial activity
Abstract
A series of novel quinoline-6-carboxamides and 2-chloroquinoline-4-carboxamides were synthesized by the reaction of their analogous carboxylic acids with various amine derivatives in the presence of base TEA and protecting agent BOP at room temperature. Synthesized compounds were confirmed by spectral characterization viz IR, 1H-NMR, and MS. Antibacterial activity carried out against Escherichia coli and Staphyllococcus aureus indicated that the synthesized compounds were active against these microorganisms.
Page
241 - 245
Full Text
PDF