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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 57, Number 2
JKCSEZ 57(2)
April 20, 2013

Title	Design, Synthesis and Antibacterial Activity Studies of Novel Quinoline Carboxamide Derivatives
Author	Yellappa Shivaraj, Malenahalli H Naveen, Giriyapura R Vijayakumar*, Doyijode B Aruna Kumar
Keywords	Quinoline-6-carboxamides, 2-Chloro quinoline-4-carboxamides, Antibacterial activity
Abstract	A series of novel quinoline-6-carboxamides and 2-chloroquinoline-4-carboxamides were synthesized by the reaction of their analogous carboxylic acids with various amine derivatives in the presence of base TEA and protecting agent BOP at room temperature. Synthesized compounds were confirmed by spectral characterization viz IR, 1H-NMR, and MS. Antibacterial activity carried out against Escherichia coli and Staphyllococcus aureus indicated that the synthesized compounds were active against these microorganisms.
Page	241 - 245
Full Text	PDF

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