ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 49, Number 4
JKCSEZ 49(4)
August 20, 2005 

2-Ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide(7) was synthesized from benzofuroxan and ethyl acetoacetate. The reaction of compound 7 with hydrazine hydrate gave 2-hydrazinocarbonyl-3-methylquinoxaline 1,4-dioxide(8). The reactions of compound 8 with substituted phenylacetyl chlorides, benzyl chloroformate, heteroaryl aldehydes and acid anhydrides afforded 3-methyl-2-(substituted hydrazinocarbonyl)quinoxaline 4-oxides(9-12). The reaction of compound 8 with isothiocyanates afforded 3-methyl-2-[(N-substituted thiocarbamoyl)hydrazinocarbonyl]quinoxaline 4-oxides(13), and followed reflux in 2N NaOH resulted in the intramolecular cyclization to give 3-methyl-2-(4-substituted-3-thioxo-1,2,4-triazol-5-yl)quinoxaline 4-oxides(14). The herbicidal and fungicidal activities of the synthesized compounds were investigated.