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Journal of the Korean Chemical Society (JKCS)

ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 47, Number 2
JKCSEZ 47(2)
April 20, 2003 

 
Title
Synthesis and Antibacterial Activity of Some Oxazolone Derivatives

옥사졸론 유도체의 합성과 항균성
Author
M. J. Aaglawe, S. S. Dhule, S. S. Bahekar, P. S. Wakte, D. B. Shinde

M. J. Aaglawe, S. S. Dhule, S. S. Bahekar, P. S. Wakte, D. B. Shinde
Keywords
치환된 4-옥사졸-5 유도체, 항균성 합성
Abstract
일련의 옥사졸론 유도체들을 (4a-n) 항균제로서 합성하였다. 이 화합물들은 아릴옥시아세틸아미노아세트산을 에탄올, 아세트산 무수물, 아세트산 소듐 존재하에 알데하이드와 반응시켜 합성하였으며 핵자기공명 스펙트럼과 적외선 스펙트럼으로 구조를 확인하였다.

A series of oxazolone derivatives (4a-n) have been synthesized as a potential antibacterial agent. Titled compounds have been prepared by the condensation of aryloxy acetyl-amino-acetic acid with aldehyde in presence of ethanol, acetic anhydride and sodium acetate. The structures of the new compounds were established on the basis of 1H NMR and IR spectral data.

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