ISSN 1017-2548(Print)
ISSN 2234-8530(Online)
Volume 47, Number 1
JKCSEZ 47(1)
February 20, 2003 

Fibrosstatins, which were isolated from the culture broth of Streptomyces catanulae subsp. griseospora, are naphthoquinones which can work as alkylating agents. It is important to synthesize these quinone compounds for the study of their biological activities. In this paper, an efficient method, Hooker oxidation, to control the regiochemistry in the synthesis of fibrostatin B is reported.