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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 16, Number 11
BKCSDE 16(11)
November 20, 1995 

 
Title
Synthesis of N-Substituted Isoindolin-1-ones via Palladium-Catalyzed Carbonylative Heterocyclization of o-Bromobenzylbromide with Carbon Monoxide and Primary Amines
Author
Sang Chul Shim*, Li Hong Jiang, Dong Yub Lee, Chan Sik Cho
Keywords
Abstract
A convenient method for the synthesis of N-substituted isoindolin-1-ones is disclosed in palladium(0)-catalyzed heterocyclization of o-bromobenzylbromide with carbon monoxide (CO) and primary amines in DMF at 100 ℃.
Page
1064 - 1067
Full Text
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