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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 12, Number 2
BKCSDE 12(2)
February 20, 1991

Title	Total Synthesis of Fosfazinomycin A
Author	Ik Joong Kang*, Suk In Hong, Yong Joon Kim
Keywords
Abstract	Fosfazinomycin A(1), methyl valylarginylmethylhydrazinohydroxyphosphonohydro xyacetate, has been synthesized. N-Carbobenzyloxyvalylnitroarginine(6) was reacted with methyl methylhydrazinobenzyloxyphosphonobenzyloxyacet ate(10) which has carbon-phosphorus bond, to give a coupled product of methyl N-Carbobenzyloxyvalylnitroarginylmethylhydrazinob enzyloxyphosphonobenzyloxyacetate(11). The deprotection of (11) by hydrogenation yielded Fosfazinomycin A(1).
Page	127 - 130
Full Text	PDF

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