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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 11, Number 2
BKCSDE 11(2)
February 20, 1990 

 
Title
Synthesis and Biological Activities of the Alternating Copolymers Containing Cyclic Ether Rings along with Carboxyl or Hydroxyl Groups on Their Backbones
Author
Man Jung Han*, Shin Duk Kang, Won Young Lee
Keywords
Abstract
The alternating copolymers of dihydropyran(DP)-maleic anhydride(MA), dihydrofuran(DF)-MA and DF-vinylene carbonate(VC) were prepared by free radical copolymerization of DP or DF with MA or VC. The reactivity ratios for poly(DF-VC) were found to be less than unity (0.05, 0.04) and its alternating sequences were obtained by feeding an equimolar amount of the comonomers at the onset of copolymerizations. The copolymers were hydrolyzed to give poly(TP-CE), poly(TF-CE) and poly(TF-HE), whose cytotoxicities against normal and tumor cells (3LL, B16) were measured in vitro.
Page
154 - 156
Full Text
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