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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 8, Number 3
BKCSDE 8(3)
March 20, 1987 

 
Title
Synthetic beta-Lactam Antibiotics Ⅰ. Synthesis and Antibacterial Activity of 7-Amino-3-[1-(halo-substituted phenyl)-1H-tetrazole-5-yl]thiomethyl-3-cepheme-4-carboxylic acids
Author
Dongsoo Koh, Sang-Woo Park, Youseung Kim*
Keywords
Abstract
The syntheses of mercaptotetrazoles and cephalothin analogs are described. Their in vitro potency was established. The compounds exhibited high antibacterial activity against Gram-positive bacteria and moderate activity against Gram-negative bacteria.
Page
189 - 195
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