Current time in Korea 15:26 Oct 14 (Mon) Year 2019 KCS KCS Publications
KCS Publications
My Journal Log In Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 8, Number 1
BKCSDE 8(1)
January 20, 1987 

 
Title
Liquid Chromatographic Resolution of Racemic Drugs on Various α-Arylalkylamine Derived Chiral Stationary Phases
Author
Myung Ho Hyun*, William H. Pirkle
Keywords
Abstract
After conversion to their 3,5-dinitrobenzoyl or 3,5-dinitroanilide derivatives, the enantiomers of a number of drugs may be chromatographically separated on various α-arylalkylamine-derived chiral stationary phases (CSPs). While each CSP used in this study is useful, CSP 1 is best able to resolve the 3,5-dinitroanilide derivative of Ibuprofen while CSP 9 generally gives rather large α values for the resolution of 3,5-dinitrobenzoyl derivatives of the enantiomers of β-adrenergic blocking drugs.
Page
45 - 47
Full Text
PDF