Current time in Korea 05:36 Sep 24 (Tue) Year 2019 KCS KCS Publications
KCS Publications
My Journal Log In Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 7, Number 1
BKCSDE 7(1)
January 20, 1986 

 
Title
Attempts on the Preparation of Lithium Trialkoxyborohydrides. Stability and Stereoselective Reduction of Cyclic Ketones
Author
Jin Soon Cha*, Jin Euog Kim, Jae Cheol Lee, Mal Sook Yoon
Keywords
Abstract
The reaction of potassium trialkoxyborohydrides of varying steric requirements with lithium chloride in tetrahydrofuran(THF) was examined in detail to establish the generality of this synthesis of the corresponding lithium trialkoxyborohydrides. The metal ion exchange reaction between potassium triisopropoxyborohydride and lithium chloride in THF proceeded instantly at room temperature and the corresponding lithium salt was very stable toward disproportionation. However, for R = s-Bu, t-Bu and 2-methylcyclohexyl, with increasing steric requirement, the lithium derivatives were unstable and thus dissociated into (RO)BH3- and (RO)4B-. The stereoselectivity of lithium triisopropoxyborohydride(LIPBH) in the reduction of representative cyclic ketones was examined and compared with that of the potassium derivative.
Page
66 - 69
Full Text
PDF