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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 35, Number 12
BKCSDE 35(12)
December 20, 2014 

 
Title
Synthesis of Piperidones from Benzyl Azides and Acetone
Author
Junghoon Han, Young Ho Rhee*, Jaiwook Park*
Keywords
4-Piperidone, N-Unsubstituted imine, Benzyl azide, Synthetic method
Abstract
A new method for the synthesis of 2,2-dimethyl-6-substituted 4-piperidone was developed; two equivalents of acetone were annulated with N-unsubstituted imines in-situ generated from benzyl azides using a ruthenium catalyst in the presence of L-proline.
Page
3433 - 3436
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