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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 35, Number 11
BKCSDE 35(11)
November 20, 2014

Title	A Quinoline-thiooxorhodamine Conjugate for Fluorescent Hg²⁺ Recognition in Aqueous Media and Living Cells
Author	Lijun Tang*, Xin Wen, Xin Dai, Di Wu, Zhenlong Huang
Keywords	Fluorescence, Hg(II) recognition, Rhodamine, Cell imaging
Abstract	A quinoline-thiooxorhodamine conjugate fluorescent sensor (1) has been synthesized. Sensor 1 exhibits high selectivity and sensitivity to Hg2+ in H2O/DMSO (95/5, v/v, HEPES 20 mM, pH = 7.4) solution with fluorescence detection. Other tested metal ions do not induce any significant fluorescence intensity changes. Sensor 1 interacts with Hg2+ through a 1:1 binding stoichiometry with a good anti-inference ability. In addition, fluorescent imaging of Hg2+ in Hela cells is also successfully demonstrated.
Page	3326 - 3330
Full Text	PDF / Supporting Information

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