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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 35, Number 10
BKCSDE 35(10)
October 20, 2014 

Butyrolactones Derivatives from the Fermentation Products of an Endophytic Fungus Aspergillus versicolor
Yan-qing Ye, Cong-Fang Xia, Juan-Xia Yang, Yu-Chun Yang, Ying Qin, Xue-Mei Gao, Gang Du, Xue-Mei Li*, Qiu-Fen Hu*
Butyrolactones, Aspergillus versicolor, Structure elucidation, Anti-TMV activity
Two new butyrolactones, asperphenol A (1) and B (2), together with four known butyrolactones (3-6) were isolated from the fermentation products of an endophytic fungus Aspergillus versicolor. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compounds 1-6 were also tested for their anti-tobacco mosaic virus (anti-TMV) activities. The results showed that compound 2 exhibited high anti-TMV activity with inhibition rate of 46.7%. The other compounds also exhibited potential anti-TMV activities with inhibition rates in the range of 21.8-28.4%.
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