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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 35, Number 8
BKCSDE 35(8)
August 20, 2014 

A Coumarin-based Fluorescent Sensor for Selective Detection of Copper (II)
Jian-Hong Wang*, Xin-Ling Guo, Xu-Feng Hou, Hui-Jun Zhao, Zhao-Yang Luo, Jin Zhao
Coumarin, Cu2+ detection, Confocal fluorescent, Biological imaging
Cu (II) detection is of great importance owing to its significant function in various biological processes. In this report, we developed a novel coumarin-based chemosensor bearing the salicylaldimine unit (2) for Cu2+ selective detection. The results from fluorescence spectra demonstrated that the sensor could selectively recognize Cu2+ over other metal cations and the detection limit is as low as 0.2 μM. Moreover, the confocal fluorescence imaging in HepG2 cells illustrated its potential for biological applications.
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