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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 34, Number 8
BKCSDE 34(8)
August 20, 2013 

An Efficient Method for Multicomponent Synthesis of Spiro[4H-pyran-oxindole] Derivatives Catalyzed by Magnesium Perchlorate
Chunlei Wu, Runpu Shen*, Jianhui Chen, Chunqi Hu
Multicomponent synthesis, Isatin, Spiro[4H-pyran-oxindole], Magnesium perchlorate
A simple and efficient method for the synthesis of spiro[4H-pyran-oxindole] derivatives by means of threecomponent reactions between isatins, malononitrile or ethyl cyano-acetate, and 1,3-dicarbonyl compounds in the presence of catalytic amount of magnesium perchlorate in 50% aqueous ethanol medium has been described.
2431 - 2435
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