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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 33, Number 5
BKCSDE 33(5)
May 20, 2012 

A Simple and Efficient One-Pot Three-Component Synthesis of Propargylamines Using Bismuth (III) Chloride
Abbas Teimouri,* Alireza Najafi Chermahini, M. Narimani
Bismuth (III) chloride, Green synthesis, Propargylamines, Three component reaction
A simple highly versatile and efficient method has been developed for the three-component coupling of aldehydes, amines and alkynes to prepare propargylamines, in the presence of a catalytic amount of BiCl3. The advantages of methods are high yield, mild reaction conditions, no environmental pollution and easy work up procedure.
1556 - 1560
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