Current time in Korea 08:05 Nov 26 (Thu) Year 2020 KCS KCS Publications
KCS Publications
My Journal  Log In  Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 33, Number 2
BKCSDE 33(2)
February 20, 2012 

Discovery of Novel 1,4-Benzodioxane Containing Thiazolidinone Derivatives as Potential Antihepatotoxic Agent
Habibullah Khalilullah,*, Shamshir Khan, Mohamed Jawed Ahsan, Bahar Ahmed
1,4-Benzodioxane, Thiazolidinone, Antihepatotoxic activity
In continuance of our search for newer antihepatotoxic agents some novel thiazolidinone derivatives containing 1,4-benzodioxane ring system were synthesized starting from 2,3-dihydro-1,4-benzodioxane-2-carbohydrazide. The synthesized compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Among them some compounds have shown significant antihepatotoxic activity comparable to standard drug silymarin.
575 - 582
Full Text
PDF / Supporting Information