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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 32, Number 8
BKCSDE 32(8)
August 20, 2011

Title	CdTe Quantum Dots as Fluorescent Probes for Josamycin Determination
Author	Jinyun Peng*, Keliang Nong, Guangshan Mu, Fengying Huang
Keywords	Quantum dots, Josamycin, Fluorescence quenching, Determination
Abstract	A new method for the determination of josamycin has been developed based on quenching of the fluorescence of 3-mercaptopropionic acid-capped CdTe quantum dots (MPA-CdTe QDs) by josamycin in ethanol. Reaction time, interfering substances on the fluorescence quenching, and mechanism of the interaction of CdTe QDs with josamycin were investigated. Under optimum conditions, the relative fluorescence intensity was linearly proportional to the concentration of josamycin between 12.0 and 120.0 μg mL−1 with a correlation coefficient of 0.9956 and a detection limit of 2.5 μg mL−1. The proposed method was successfully applied to commercial tablets, and the results were satisfactory, i.e. consistent with those of high-performance liquid chromatography (HPLC).
Page	2727 - 2731
Full Text	PDF

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