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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 32, Number 4
BKCSDE 32(4)
April 20, 2011 

 
Title
Selective Determination of Serotonin on Poly(3,4-ethylenedioxy pyrrole)-single-walled Carbon Nanotube-Modified Glassy Carbon Electrodes
Author
Seul Ki Kim, Si Ra Bae, Mohammad Shamsuddin Ahmed, Jung Min You, Seungwon Jeon *
Keywords
3,4-Ethylenedioxy pyrrole, Single-walled carbon nanotubes, Serotonin, Modified electrode, Biosensor
Abstract
An electrochemically-modified electrode [P(EDOP-SWNTs)/GCE] was prepared by electropolymerization of 3,4-ethylenedioxy pyrrole (EDOP) single-walled carbon nanotubes (SWNTs) on the surface of a glassy carbon electrode (GCE) and characterized by SEM, CV, and DPV. This modified electrode was employed as an electrochemical biosensor for the selective determination of serotonin concentrations at pH 7.4 and exhibited a typical enhanced effect on the current response of serotonin with a lower oxidation overpotential. The linear response was in the range of 1.0 × 10−7 to 1.0 × 10−5 M, with a correlation coefficient of 0.998 on the anodic current. The lower detection limit was calculated as 5.0 nM. Due to the relatively low currents and difference of potentials in the electrochemical responses of uric acid (UA), ascorbic acid (AA), and dopamine (DA), the modified electrode was a useful and effective sensing device for the selective and sensitive serotonin determination in the presence of UA, AA, and DA.
Page
1215 - 1220
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