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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 31, Number 8
BKCSDE 31(8)
August 20, 2010 

 
Title
New Compounds from Euphorbia helioscopia and Absolute Configuration Determination by Computational Methods
Author
Jiangbo He, Hua Jie Zhu, Gui Fen Luo, Guang Ming Liu, Hao Chen, Yan Li, Shaopeng Chen, Xin Lu, Guochun Zhou, Yong Xian Cheng*
Keywords
Euphorbia helioscopia, Euphorbiaceae, Lactam, Terpenoids, Quantum calculations
Abstract
The whole plant of Euphorbia helioscopia is an important traditional Chinese medicine. Fom its BuOH soluble extract, one new lactam (1), three new terpenoids (2-4) including a new naturally occurring compound, and three known compounds were isolated. Their structures were identified by spectroscopic evidences. In particular, the absolute configurations of side chain of compounds 1 and 2 were determined using computational methods.
Page
2211 - 2214
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