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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 31, Number 4
BKCSDE 31(4)
April 20, 2010 

 
Title
Synthesis and Antibacterial Evaluation of Some Novel 2-Arylamino-4-phenyl-thiazolyl Derivatives
Author
Kokila A Parmar*, Bharat G Suthar, Sarju Parajapati
Keywords
Thiazole, 2-Amino-4-phenyl-thiazolyl, Antibacterial activity, MIC
Abstract
A series of 2-aminothiazoles derivatives have been synthesized and tested for in vitro antibacterial activity on different microorganisms. Syntheses have been carried out following simple methodology in excellent isolated yields. The structure and purity of the original compounds were confirmed by IR, NMR, Mass spectroscopy, and elemental analysis. All compounds were tested for antibacterial activity against S. aureus, S. pyogenes, E. coli, P. aeruginosa, S. typhi and V. parahaemolyticus. These preliminary results indicate that some of compounds are exhibiting good activity.
Page
793 - 797
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