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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 30, Number 5
BKCSDE 30(5)
May 20, 2009 
 
Title
 Synthesis of 3'(β)-C-methyl Carbodine Analogues as Potential Anti-HCV Agents
Author
 Hua Li, Young Chan Baik, Joon Hee Hong*
Keywords
 Carbodine, Anti-HCV agents, Ring-closing metathesis, Vicinal dihydroxylation
Abstract
 The synthetic route of novel 3′-C-methyl carbodine analogue is described. The construction of tertiary alcohol at 3′-position of carbodine analogues was successfully made via sequential [3,3]-sigmatropic rearrangement, ring-closing metathesis (RCM) and stereoselective dihydroxylation reactions starting from ethyl glycolate.
Page
 1147 - 1151
Full Text
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