Current time in Korea 23:49 Apr 19 (Fri) Year 2024 KCS KCS Publications
KCS Publications
My Journal  Log In  Register
HOME > Search > Browsing(BKCS) > Archives

Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 30, Number 2
BKCSDE 30(2)
February 20, 2009 
 
Title
 Effect of Hydrogenated Lecithin on Cytotoxicity of Liposome
Author
 Duck Hwan Bae, Jae Sup Shin, Fan Long Jin, Gwi Su Shin, Soo Jin Park*
Keywords
 Lecithin, Liposome, Particle size, Turbidity, Cytotoxicity
Abstract
 In this study, a hydrogenated lecithin-containing liposome was prepared using a sonicator and microfluidizer at high shear. The surface tension, particle size, turbidity, and transition temperature (Tc) of the liposome were investigated and compared with the commercially available standard surfactant Tween-60. The cytotoxicities were characterized using the MTT method. The surface tension of hydrogenated lecithin was found to be higher than that of Tween-60. The particle size prepared at above Tc was smaller than that prepared below Tc. The results of the cytotoxicity experiment indicated that Lecinol 10 exhibits the highest IC50 value, which shows its high safety in this study.
Page
 339 - 342
Full Text
 PDF

How to access to the WOL for The Bulletin of the Korean Chemical Society ?

The Bulletin of the Korean Chemical Society will be co-published with Wiley-VCH from 2015 towards. The online version of the Journal will thus be available on Wiley Online Library, Wiley(-VCH)'s global online platform.

KCS members can get a free online access to the Bulletin of the Korean Chemical Society in WOL.

Close