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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 29, Number 6
BKCSDE 29(6)
June 20, 2008 

 
Title
Concise Total Synthesis of Biologically Interesting Prenylated Chalcone Natural Products: 4'-O-Methylxanthohumol, Xanthohumol E, and Sericone
Author
Yong Rok Lee*, Xin Li, Seung Woo Lee, Chul Soon Yong, Ma-Ro Hwang, Won Seok Lyoo
Keywords
Prenylated chalcone, Xanthohumol, 4'-O-Methylxanthohumol, Xanthohumol E, Sericone
Abstract
A new and efficient synthetic approach is reported for biologically interesting prenylated chalcones, 4'-Omethylxanthohumol (3), xanthohumol E (4), and sericone (5) from 2,4,6-trihydroxyacetophenone. The strategies involve the introduction of a prenyl group onto an aryl ring, benzopyran formation, and basecatalyzed aldol reactions.
Page
1205 - 1210
Full Text
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