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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 27, Number 9
BKCSDE 27(9)
September 20, 2006 

Structure and Biological Activity of K(H2O)L (L = 5,7-Dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate)
Ya-Ning Guo, Xue-Ling Zhang, Zun-Ting Zhang*
5,7-Dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate, Irisolidone, Crystal structure, Biological activity
Potassium(I) with 5,7-dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate (L) assembles to K(H2O)L (L = 5,7-dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate). It was characterized by single-crystal X-ray diffraction, element analysis, IR and 1H NMR spectroscopy. It crystallizes in the monoclinic space group P21/n and reveals a seven-coordinate complex. Polyhedra potassium chains, C-H···π and C-H···O and O-H···O hydrogen bonds lead K(H2O)L to a three-dimensional network structure. The biological activity of resistance to hypoxia was tested, and the results showed that the biological activity of resistance to hypoxia of K(H2O)L is as good as that of its precursor, irisolidone.
1289 - 1292
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