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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 25, Number 1
BKCSDE 25(1)
January 20, 2004 

 
Title
A Novel Route to New Bis(benzopyrano) Fused Dihydropyridines Using Dry Media
Author
Mazaahir Kidwai*, Shweta Rastogi, Richa Mohan
Keywords
Benzopyran, Pyridine, Solid support, Microwave irradiation, Ecofriendly
Abstract
A new and efficient synthesis of the novel bioactive bis(benzopyrano) fused dihydropyridines is described. The conventionally developed route is a two step multicomponent condensation reaction. This is latter modified by a one pot microwave (MW) assisted reaction using inorganic solid support via the arylidene derivative intermediate. With this environmentally benign approach, the reaction time is brought down from hours to minutes along with a yield enhancement. Furthermore, the role of different solid supports is studied and it is concluded that the acidic alumina is the best solid support for the present investigation.
Page
119 - 121
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